Intermediate, Posterior, and Panuveitis*
Non-Infectious Uveitis

Why consider HUMIRA for non-infectious uveitis*?

HUMIRA can help control non-infectious uveitis*.

HUMIRA was proven to help control non-infectious uveitis. There were three measurements used to assess whether a patient was flaring and one that evaluated blurry vision:

  • Vitreous haze (cloudiness in the middle of the eye)
  • Inflammatory cells in the front of the eye
  • New lesions on the retina
  • Maintenance of visual clarity (how well you see at a distance)

In a clinical study, HUMIRA was shown to increase the time that non-infectious uveitis* was controlled.

Some patients experienced 50% decreased risk of a flare and loss of visual clarity. Result may vary.

HUMIRA patients with active disease experienced 50% decreased risk of a combination of flare and loss of visual clarity.

Some patients experienced differences in disease control in as early as 6 weeks with HUMIRA® (adalimumab) for uveitis. Results may vary.

Differences in disease control as early as week 6 for patients taking HUMIRA.

FDA-approved biologic to treat noninfectious intermediate, posterior, and panuveitis

HUMIRA is a different way to treat uveitis*.

HUMIRA is the first and only biologic proven to treat non-infectious intermediate, posterior, and panuveitis in adult patients.

HUMIRA is a whole different way to treat non-infectious uveitis*. It is not a steroid.

HUMIRA works by targeting and blocking a specific source of inflammation that plays a role in non-infectious uveitis*.

HUMIRA can treat different types of non-infectious uveitis* that cause inflammation in different parts of the eye.

HUMIRA® (adalimumab) has been studied for over 14 years, backed by clinical testing & research

Prescribed to treat inflammatory conditions for over 14 years.

HUMIRA was approved to treat non-infectious uveitis* fairly recently. But it was first approved to treat an inflammatory condition over 14 years ago and over time has been approved to treat a total of 10 inflammatory diseases.

Treating and managing non-infectious uveitis* can take teamwork.

It can take more than one doctor or specialist to manage your non-infectious uveitis*.

You may start by seeing an ophthalmologist. But it's likely you'll also see a retinal specialist, uveitis specialist, or a rheumatologist as part of your treatment plan.

Retinal specialists and uveitis specialists are ophthalmologists with special training. Rheumatologists specialize in treating inflammation in the body. Because non-infectious uveitis is caused by inflammation, a rheumatologist can play a key part in determining the right treatment.

A biologic may be prescribed to control your disease. Your ophthalmologist, retinal specialist, or uveitis specialist will then monitor the progress of your treatment alongside your rheumatologist. Change in your eyes may require changes in your medication. Always tell your doctor about all medications you are taking.

Prepping for your doctor visit is important.

It’s important to make the most of your time with your doctor so you can get the information you need to manage your non-infectious uveitis* treatment. You can come prepared with a list of questions for your doctor. And your doctor will have questions for you, too.

You may consider asking your doctor:

  • Have you treated other patients with non-infectious intermediate, posterior, or panuveitis?
  • Will I need an additional doctor to treat my type of uveitis?
  • Might a biologic be right for me?

Your doctor may ask you:

  • What are your symptoms and when did they start?
  • What treatments have you already been prescribed?
  • Have your symptoms worsened?

When visiting your doctors, a second set of eyes—and ears—can be helpful.

You may want to bring someone to help remind you to ask certain questions and take notes.

HUMIRA Complete gives you the resources you need—when you need them.

Enrolling in HUMIRA Complete offers access to all the resources you need to start and stay on HUMIRA as prescribed by your doctor, at no additional cost to you.

Connect with a HUMIRA® (adalimumab) Nurse Ambassador for patient assistance

Your HUMIRA Nurse Ambassador is there for you.

At the heart of HUMIRA Complete is your personal Nurse Ambassador, a registered nurse who will be there to listen, answer questions, and get to know you.

Your Nurse Ambassador can:

  • Help you identify ways to save on HUMIRA, month after month
  • Provide additional injection training
  • Work with you to establish a routine with HUMIRA

Learn more about HUMIRA Complete and how to get your own Nurse Ambassador.

Nurse Ambassadors do not give medical advice and will direct you to your health care professional for any treatment-related questions, including further referrals.

Next Page: How HUMIRA Works

Your safety is important to us.
Learn about our Important Safety Information.

IMPORTANT SAFETY INFORMATION
ABOUT HUMIRA® (adalimumab)1

What is the most important information I should know about HUMIRA?

You should discuss the potential benefits and risks of HUMIRA with your doctor. HUMIRA is a TNF blocker medicine that can lower the ability of your immune system to fight infections. You should not start taking HUMIRA if you have any kind of infection unless your doctor says it is okay.

  • Serious infections have happened in people taking HUMIRA. These serious infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some people have died from these infections. Your doctor should test you for TB before starting HUMIRA, and check you closely for signs and symptoms of TB during treatment with HUMIRA, even if your TB test was negative. If your doctor feels you are at risk, you may be treated with medicine for TB.

  • Cancer. For children and adults taking TNF blockers, including HUMIRA, the chance of getting lymphoma or other cancers may increase. There have been cases of unusual cancers in children, teenagers, and young adults using TNF blockers. Some people have developed a rare type of cancer called hepatosplenic T-cell lymphoma. This type of cancer often results in death. If using TNF blockers including HUMIRA, your chance of getting two types of skin cancer (basal cell and squamous cell) may increase. These types are generally not life-threatening if treated; tell your doctor if you have a bump or open sore that doesn’t heal.


What should I tell my doctor BEFORE starting HUMIRA?

Tell your doctor about all of your health conditions, including if you:

  • Have an infection, are being treated for infection, or have symptoms of an infection
  • Get a lot of infections or infections that keep coming back
  • Have diabetes
  • Have TB or have been in close contact with someone with TB, or were born in, lived in, or traveled where there is more risk for getting TB
  • Live or have lived in an area (such as the Ohio and Mississippi River valleys) where there is an increased risk for getting certain kinds of fungal infections, such as histoplasmosis, coccidioidomycosis, or blastomycosis. These infections may happen or become more severe if you use HUMIRA. Ask your doctor if you are unsure if you have lived in these areas.
  • Have or have had hepatitis B
  • Are scheduled for major surgery
  • Have or have had cancer
  • Have numbness or tingling or a nervous system disease such as multiple sclerosis or Guillain-Barré syndrome
  • Have or had heart failure
  • Have recently received or are scheduled to receive a vaccine. HUMIRA patients may receive vaccines, except for live vaccines. Children should be brought up to date on all vaccines before starting HUMIRA.
  • Are allergic to rubber, latex, or any HUMIRA ingredients
  • Are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed
  • Have a baby and you were using HUMIRA during your pregnancy. Tell your baby’s doctor before your baby receives any vaccines

Also tell your doctor about all the medicines you take. You should not take HUMIRA with ORENCIA® (abatacept), KINERET® (anakinra), REMICADE® (infliximab), ENBREL® (etanercept), CIMZIA® (certolizumab pegol), or SIMPONI® (golimumab). Tell your doctor if you have ever used RITUXAN® (rituximab), IMURAN® (azathioprine), or PURINETHOL® (mercaptopurine, 6-MP).


What should I watch for AFTER starting HUMIRA?

HUMIRA can cause serious side effects, including:

  • Serious infections. These include TB and infections caused by viruses, fungi, or bacteria. Symptoms related to TB include a cough, low-grade fever, weight loss, or loss of body fat and muscle.
  • Hepatitis B infection in carriers of the virus. Symptoms include muscle aches, feeling very tired, dark urine, skin or eyes that look yellow, little or no appetite, vomiting, clay-colored bowel movements, fever, chills, stomach discomfort, and skin rash.
  • Allergic reactions. Symptoms of a serious allergic reaction include hives, trouble breathing, and swelling of your face, eyes, lips, or mouth.
  • Nervous system problems. Signs and symptoms include numbness or tingling, problems with your vision, weakness in your arms or legs, and dizziness.
  • Blood problems (decreased blood cells that help fight infections or stop bleeding). Symptoms include a fever that does not go away, bruising or bleeding very easily, or looking very pale.
  • Heart failure (new or worsening). Symptoms include shortness of breath, swelling of your ankles or feet, and sudden weight gain.
  • Immune reactions including a lupus-like syndrome. Symptoms include chest discomfort or pain that does not go away, shortness of breath, joint pain, or rash on your cheeks or arms that gets worse in the sun.
  • Liver problems. Symptoms include feeling very tired, skin or eyes that look yellow, poor appetite or vomiting, and pain on the right side of your stomach (abdomen).
  • Psoriasis (new or worsening). Symptoms include red scaly patches or raised bumps that are filled with pus.

Call your doctor or get medical care right away if you develop any of the above symptoms.


Common side effects of HUMIRA include injection site reactions (redness, rash, swelling, itching, or bruising), upper respiratory infections (sinus infections), headaches, rash, and nausea. These are not all of the possible side effects with HUMIRA. Tell your doctor if you have any side effect that bothers you or that does not go away.


Remember, tell your doctor right away if you have an infection or symptoms of an infection, including:

  • Fever, sweats, or chills
  • Muscle aches
  • Cough
  • Shortness of breath
  • Blood in phlegm
  • Weight loss
  • Warm, red, or painful skin or sores on your body
  • Diarrhea or stomach pain
  • Burning when you urinate
  • Urinating more often than normal
  • Feeling very tired

HUMIRA is given by injection under the skin.


This is the most important information to know about HUMIRA. For more information, talk to your health care provider.

 

Uses

 

HUMIRA is a prescription medicine used:

  • To reduce the signs and symptoms of:
    • Moderate to severe rheumatoid arthritis (RA) in adults. HUMIRA can be used alone, with methotrexate, or with certain other medicines. HUMIRA may prevent further damage to your bones and joints and may help your ability to perform daily activities.
    • Moderate to severe polyarticular juvenile idiopathic arthritis (JIA) in children 2 years of age and older. HUMIRA can be used alone, with methotrexate, or with certain other medicines.
    • Psoriatic arthritis (PsA) in adults. HUMIRA can be used alone or with certain other medicines. HUMIRA may prevent further damage to your bones and joints and may help your ability to perform daily activities.
    • Ankylosing spondylitis (AS) in adults.
    • Moderate to severe Crohn's disease (CD) and to achieve and maintain clinical remission in adults who have not responded well to certain other medications. HUMIRA is also used to reduce signs and symptoms and to achieve clinical remission in these adults who have lost response to or are unable to tolerate infliximab.
    • Moderate to severe Crohn's disease (CD) and to achieve and maintain clinical remission in children 6 years of age and older when certain other treatments have not worked well enough.
    • Moderate to severe hidradenitis suppurativa (HS) in adults.
  • In adults, to help get moderate to severe ulcerative colitis (UC) under control (induce remission) and keep it under control (sustain remission) when certain other medicines have not worked well enough. It is not known if HUMIRA is effective in people who stopped responding to or could not tolerate anti-TNF medicines.
  • To treat moderate to severe chronic plaque psoriasis (Ps) in adults who are ready for systemic therapy or phototherapy, and are under the care of a doctor who will decide if other systemic therapies are less appropriate.
  • To treat non-infectious intermediate (middle part of the eye), posterior (back of the eye) and panuveitis (all parts of the eye) (UV) in adults.

64H-1880706

In This Section

Find a doctor with uveitis treatment experience with HUMIRA® (adalimumab)

Not every doctor has experience treating uveitis.

Find One Who Does

Please see the Full Prescribing Information, including the Medication Guide, for HUMIRA.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

If you cannot afford your medication, contact: www.pparx.org for assistance.

Please see accompanying full Prescribing Information, including Patient Instructions for Use in the Medication Guide and discuss it with your doctor.

Legal Notices/Privacy Policy. Copyright 2013, AbbVie Inc., North Chicago, Illinois, U.S.A. If you have any questions about AbbVie’s HUMIRA.com website that have not been answered click here. This website and the information contained herein is intended for use by US residents only, is provided for informational purposes only and is not intended to replace a discussion with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider and consider the unique characteristics of each patient.

Reference: 1. HUMIRA Injection [package insert]. North Chicago, IL: AbbVie Inc.

1299985-1860304


Information from AbbVie

HUMIRA Use1

HUMIRA is a prescription medicine used to treat non-infectious intermediate (middle part of the eye), posterior (back of the eye) and panuveitis (all parts of the eye) in adults.

SAFETY CONSIDERATIONS1

Serious infections have happened in people taking HUMIRA. These serious infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some people have died from these infections. HUMIRA may increase the chance of getting lymphoma, including a rare kind, or other cancers. HUMIRA can cause serious side effects including hepatitis B infection in carriers of the virus, allergic reactions, nervous system problems, blood problems, heart failure, certain immune reactions including a lupus-like syndrome, liver problems, and new or worsening psoriasis.