One factor involved in your child's Crohn's disease is producing too much of a protein called TNF. This overproduction of TNF can cause your child's gastrointestinal tract to become inflamed, which can trigger Crohn’s symptoms.
Crohn's symptoms can include abdominal pain/cramping and diarrhea, and are the result of inflammation in the gastrointestinal (GI) tract. Complications (different types of bowel injury) can also develop if the inflammation is persistent.
Symptoms are unpredictable and often depend on the level of severity as well as location of inflammation, which could be anywhere in the gastrointestinal tract from the mouth to the anus, including the stomach and intestines. This is why it’s always important to talk to your child about any of the symptoms of pediatric Crohn’s disease that they may be experiencing.
Since each person is different, Crohn’s does not progress in the same way for everyone. Symptoms can be similar to other GI disorders that may make Crohn's difficult to diagnose. Pediatric Crohn’s disease symptoms can include:
The goals of pediatric Crohn's disease management include achieving remission (few or no symptoms) and maintaining remission. HUMIRA is a prescription medicine used to reduce signs and symptoms, and to achieve and maintain clinical remission in children 6 years of age and older with moderate to severe Crohn’s disease when certain other treatments have not worked well enough.
To help provide education about the disease and HUMIRA, we offer you and your child a HUMIRA Ambassador at no additional cost. Your Ambassador can help teach you and your child about pediatric Crohn's disease and provide you with tools to help manage your child's condition, as well as other services and insights. To connect with a HUMIRA Ambassador, call 1.800.4HUMIRA today (select the option to speak with a nurse).
You should discuss the potential benefits and risks of HUMIRA with your doctor. HUMIRA is a TNF blocker medicine that can lower the ability of your immune system to fight infections. You should not start taking HUMIRA if you have any kind of infection unless your doctor says it is okay.
Serious infections have happened in people taking HUMIRA. These serious infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some people have died from these infections. Your doctor should test you for TB before starting HUMIRA, and check you closely for signs and symptoms of TB during treatment with HUMIRA, even if your TB test was negative. If your doctor feels you are at risk, you may be treated with medicine for TB.
Cancer. For children and adults taking TNF blockers, including HUMIRA, the chance of getting lymphoma or other cancers may increase. There have been cases of unusual cancers in children, teenagers, and young adults using TNF blockers. Some people have developed a rare type of cancer called hepatosplenic T-cell lymphoma. This type of cancer often results in death. If using TNF blockers including HUMIRA, your chance of getting two types of skin cancer (basal cell and squamous cell) may increase. These types are generally not life-threatening if treated; tell your doctor if you have a bump or open sore that doesn’t heal.
Tell your doctor about all of your health conditions, including if you:
Also tell your doctor about all the medicines you take. You should not take HUMIRA with ORENCIA® (abatacept), KINERET® (anakinra), REMICADE® (infliximab), ENBREL® (etanercept), CIMZIA® (certolizumab pegol), or SIMPONI® (golimumab). Tell your doctor if you have ever used RITUXAN® (rituximab), IMURAN® (azathioprine), or PURINETHOL® (mercaptopurine, 6-MP).
HUMIRA can cause serious side effects, including:
Call your doctor or get medical care right away if you develop any of the above symptoms.
Common side effects of HUMIRA include injection site reactions (pain, redness, rash, swelling, itching, or bruising), upper respiratory infections (sinus infections), headaches, rash, and nausea. These are not all of the possible side effects with HUMIRA. Tell your doctor if you have any side effect that bothers you or that does not go away.
HUMIRA is given by injection under the skin.
HUMIRA is a prescription medicine used:
Pediatric Crohn's Disease Symptoms
HUMIRA is a prescription medicine used to reduce signs and symptoms, and to achieve and maintain clinical remission in children 6 years of age and older with moderate to severe Crohn’s disease when certain other treatments have not worked well enough.
Serious infections have happened in people taking HUMIRA. These serious infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some people have died from these infections. HUMIRA may increase the chance of getting lymphoma, including a rare kind, or other cancers. HUMIRA can cause serious side effects including hepatitis B infection in carriers of the virus, allergic reactions, nervous system problems, blood problems, heart failure, certain immune reactions including a lupus-like syndrome, liver problems, and new or worsening psoriasis.