Learn how HUMIRA works for moderate to severe
polyarticular juvenile idiopathic arthritis.

See how HUMIRA works.

Watch this short video to get a better understanding of how HUMIRA targets and blocks TNF, a specific source of inflammation that contributes to polyarticular juvenile idiopathic arthritis (JIA) symptoms.

Many JIA symptoms may be caused by inflammation.

One factor involved in juvenile idiopathic arthritis is the production of too much of a protein called tumor necrosis factor (TNF). Some children with JIA have too much TNF in the affected joints. This extra TNF can cause inflammation, which can contribute to the joint pain, swelling, and stiffness of JIA.

HUMIRA: A biologic that targets TNF.

The immune system can overproduce a protein called TNF, one source of inflammation. HUMIRA targets and blocks TNF-alpha, one of the sources of joint pain, stiffness, and swelling.

A mom and her daughter at the doctor's office.

Ask your child's doctor about the benefits and risks of HUMIRA.

Talk to your child’s pediatric rheumatologist about the benefits and risks of taking a biologic medication. Prescription medications, including HUMIRA, have possible risks involved with treatment, so it's important to discuss them with your child's doctor. If your child is still experiencing symptoms of moderate to severe polyarticular JIA despite current treatment, ask your child's doctor about HUMIRA.

HUMIRA is not right for everyone.

Safety considerations.

Because HUMIRA blocks the action of TNF-alpha, it can lower the ability of your child’s immune system to fight infections. Your child should not start taking HUMIRA if he or she has any kind of infection unless the child’s doctor says it’s okay. People treated with HUMIRA have an increased chance of developing serious infections that may lead to hospitalization or death, and may increase the chance of getting lymphoma (including a rare kind), skin or other cancers. You should discuss the potential benefits and risks of HUMIRA with your child’s doctor.