What is HUMIRA Citrate-free?

HUMIRA Citrate-free works the same as original HUMIRA, but with less pain immediately following injection.* The active ingredient (adalimumab) is the same as it has been for over 15 years. 

If you are interested in getting started with HUMIRA Citrate-free, ask your doctor for about a prescription. 

*Compared to HUMIRA 40 mg/0.8 mL.

Already taking original HUMIRA and ready to transition to HUMIRA Citrate-free?

If you and your doctor decide together that HUMIRA Citrate-free is right for you, you will need to start a new prescription. You will not be automatically transitioned to HUMIRA Citrate-free.

HUMIRA Citrate-free comes in both the HUMIRA Pen and prefilled syringe, and is injected the same way as original HUMIRA. 

Ask your doctor about a new prescription when you are ready for your next HUMIRA refill. 

HUMIRA Citrate-free packaging

Packaging for HUMIRA Citrate-free may vary depending on the inventory of your specialty pharmacy.  The easiest way to tell the difference between original HUMIRA and HUMIRA Citrate-free is to look for the 29-gauge needle call-out on the front of the package. In addition, the packaging for your starting dose of HUMIRA Citrate-free may look different from the packaging for your maintenance dose. 

For more information about the HUMIRA Citrate-free packaging, call 1.800.4HUMIRA (1.800.448.6472).

Photograph of HUMIRA Citrate-free packaging

Get to know HUMIRA Citrate-free

Photograph of HUMIRA Citrate-free Pen

Changes you can’t see

Less pain, same HUMIRA
  • HUMIRA Citrate-free is less painful immediately following injection,*but works just like original HUMIRA.  
  • Citrate buffers associated with injection pain were removed.
  • The active ingredient (adalimumab) is the same as it has been for over 15 years  
Needle cover
  • The needle cover for the HUMIRA Citrate-free Pen and prefilled syringe is not made with natural rubber latex  

*Compared to HUMIRA 40 mg/0.8 mL.

Changes you can see

Updated box
  • Packaging for HUMIRA Citrate-free may vary depending on the inventory of your specialty pharmacy. Look for the 29-gauge needle call-out on the front of the box.
Thinner needle
  • Look for the “29-gauge needle” call-out on your HUMIRA Citrate-free box 
Less liquid
  • HUMIRA Citrate-free contains less liquid with the same amount of active ingredient (adalimumab) 
Redesigned Pen
  • The numbers on the caps are now white, and the HUMIRA Pen has a larger viewing window
Photograph of HUMIRA Citrate-free prefilled syringe

HUMIRA Citrate-free also comes in a prefilled syringe.  Ask your doctor about a new prescription for HUMIRA Citrate-free. 

Frequently asked questions 

HUMIRA Citrate-free dosing information for adult indications

It’s important to use the proper injection technique and follow the dosing schedule for your treatment with HUMIRA Citrate-free.

HUMIRA Complete is here for you 

Be sure to take advantage of all the other HUMIRA Complete resources available to you, including:  

  • Help finding ways to save on the cost of HUMIRA, month after month, with the HUMIRA Complete Savings Card*  
  • Assistance with further injection training over the phone, online, and/or in person 
  • Access to Insurance Specialists who can help you navigate the insurance process 

Before your next refill, ask your doctor about transitioning to HUMIRA Citrate-free. 

Example of HUMIRA Complete Savings Card

*Eligibility: Available to patients with commercial insurance coverage for HUMIRA® (adalimumab) who meet eligibility criteria. This co-pay assistance program is not available to patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law. Offer subject to change or termination without notice. Restrictions, including monthly maximums, may apply. This is not health insurance. For full Terms and Conditions, visit HUMIRASavingsCard.com or call 1.800.4HUMIRA for additional information. To learn about AbbVie’s privacy practices and your privacy choices, visit https://privacy.abbvie