What is ankylosing spondylitis (AS)?

Inflammation plays a big role.

Lower back pain is a common health problem. It is typically caused by injury or strain to the back, known as mechanical back pain. But your back pain could also be signaling a more serious condition.

Ankylosing spondylitis—pronounced ANK-ki-low-sing spon-di-LIE-tis—is a chronic inflammatory disease. AS occurs when the immune system mistakenly attacks healthy joints, mainly in the spine. This immune response causes inflammation, which contributes to pain and stiffness in these joints. This is known as inflammatory back pain. Because AS is a chronic disease, there is no known cure, and the focus is on controlling symptoms. If left untreated, over time the pain and stiffness of AS can become persistent and can occur in other parts of the body.

The AS symptom quiz will help you identify if the back pain and stiffness you’re experiencing could be ankylosing spondylitis, so you can partner with your doctor to develop a treatment plan that’s right for you.

Patients may see results in 2 weeks with HUMIRA® (adalimumab).

Learn more

Differences in two types of back pain.

Mechanical Back Pain

Caused by a specific injury or strain to the back, like lifting too much weight
Very common, occurring at least once in 85% of adults younger than 50
Alleviated by rest
Lasts less than 4-6 weeks

Inflammatory Back Pain

Caused by the immune system attacking healthy tissue, resulting in inflammation in the joints of the spine
- Back pain associated with AS is inflammatory in nature

Worsens with rest or inactivity, especially at night or early morning
Tends to be eased by exercise or movement
Back pain is chronic—lasts more than 3 months

Could you have ankylosing spondylitis?

Find out if your symptoms may point to an inflammatory condition like AS.

Take the Symptom Quiz

How long have you been experiencing back pain and stiffness?

See how others responded.

0-5 years

6-10 years

More than 10 years

Because back pain is common, it can take years for AS to be diagnosed. That’s why it’s important to identify if your back pain could be an inflammatory disease such as AS and get a proper diagnosis. Take the symptom quiz, then partner with a doctor to discuss your treatment options.