Less ankylosing spondylitis (AS) back pain and stiffness is possible in only 2 weeks.

Patients may see results in 2 weeks with HUMIRA® (adalimumab). For most, results may take 12 weeks or longer.

In a clinical study of patients using HUMIRA, some people experienced an improvement in AS back pain and stiffness in only 2 weeks. Most people saw results at 12 weeks.


Proven to help reduce the back pain and stiffness of AS.

In a clinical study, after 12 weeks, these are percentages of patients who saw at least a 20% improvement in signs and symptoms of AS.

In a clinical study, 58% of patients taking HUMIRA® (adalimumab) for ankylosing spondylitis saw improvement.
In a clinical study, 21% of patients taking placebo saw improvement in ankylosing spondylitis symptoms.

HUMIRA can help improve functional movement.

In a clinical trial, patients were asked to answer multiple questions about their ability to perform everyday activities, like:

Bending forward at the waist

Bending forward at the waist

Standing unsupported for 10 minutes without discomfort

Climbing 12-15 steps without using a handrail or walking aid

Doing a full day's worth of activities at work or at home


Are you currently using HUMIRA to treat your active AS?

Visit HUMIRA Complete for access to potential savings, personalized support, and resources to help you stay on track with your prescribed treatment plan.

Learn About HUMIRA Complete 

Interested in learning about a once-daily pill for adults with active AS who are still experiencing symptoms after trying a TNF blocker, like HUMIRA?

Learn more

How does HUMIRA work for AS?

Excess inflammation contributes to the AS back pain and stiffness you are experiencing. HUMIRA targets and blocks a specific source of inflammation that contributes to AS symptoms.