How HUMIRA Works

HUMIRA helps stop further irreversible joint damage and can improve joint pain, swelling, and stiffness in patients with moderate to severe RA.

Results of clinical studies

In a study of moderate to severe RA patients diagnosed for an average of 11 years who added HUMIRA to methotrexate:

63% of people who took HUMIRA® with methotrexate saw a 20% improvement in RA signs and symptoms

63% of people who took HUMIRA with methotrexate saw improvement in RA signs and symptoms (compared to 30% of people taking methotrexate alone).

When compared with methotrexate alone in a clinical study, more people taking HUMIRA and methotrexate saw a 20% improvement in the signs and symptoms of RA at 6 months.

In a separate study of patients with moderate to severe rheumatoid arthritis (diagnosed for less than three years and not previously treated with methotrexate), combining HUMIRA and methotrexate showed:

64% of people taking HUMIRA with methotrexate had no further joint damage as seen on X-ray 1 year after treatment (compared to 37% of people taking methotrexate alone).

64% of people taking HUMIRA® with methotrexate had no further joint damage as seen on X-ray 1 year after treatment

HUMIRA and methotrexate—five times more effective at slowing the progression of joint damage

HUMIRA® and methotrexate were 5 times more effective at slowing the progression of joint damage

In the same study, the combination of HUMIRA and methotrexate, on average, was 5 times more effective at slowing the progression of joint damage than methotrexate alone after 2 years.

If you have rheumatoid arthritis, seeing a rheumatologist is recommended

Moderate to Severe Rheumatoid Arthritis

Once joint damage occurs, it can’t be undone.

That’s why it’s important to get an expert opinion. Discussing details with your rheumatologist about how RA affects your daily life will help you and your doctor decide on a course of action.

Do you know your treatment options?

Learn about another treatment for moderate to severe RA that may be right for you.

A little prep may lead to a better conversation with your doctor.

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