Psoriasis has been linked to an overproduction of certain proteins, including one called TNF-alpha, which can cause inflammation. HUMIRA is a TNF-alpha blocker. It binds to TNF-alpha and helps reduce inflammation that can cause plaque psoriasis skin symptoms.
The exact cause is unknown, but plaque psoriasis has been linked to the immune system and an excess of several proteins in the body, including one called TNF-alpha. Everybody produces TNF-alpha, but people with plaque psoriasis produce more than normal. Too much TNF-alpha speeds up the growth cycle of skin cells, which can lead to the plaques—red, flaky patches—you see on your skin.