HUMIRA® (adalimumab) Citrate-free for Pediatric Crohn's Disease

Feminine teenager smiling beside HUMIRA Citrate-free call-out

*Compared to HUMIRA 40mg/0.8 mL.

The same HUMIRA you’ve come to count on has been redesigned with your child in mind.

Changes you can’t see

Ingredients

Citrate buffers associated with pain on injection, and other inactive ingredients, have been removed
The active ingredient is the same as it has been for over 15 years

Needle cover not made with natural rubber latex for both the HUMIRA Pen and prefilled syringe

Changes you can see

Photograph of the HUMIRA Citrate-free pen and syringe

A thinner needle is just the beginning

29-gauge vs 27-gauge

50% less liquid inside

Same size HUMIRA Pen and prefilled syringe
Same amount of HUMIRA active ingredient
Half the amount of liquid to inject

Redesigned Pen Cap

You will notice the numbers on the caps are now white

Larger Pen Window

The HUMIRA Pen now has a larger viewing window

Look for updated HUMIRA packaging

You may notice small updates to the HUMIRA packaging

HUMIRA Citrate-free packaging

Packaging for HUMIRA Citrate-free may vary depending on the inventory of your specialty pharmacy. Look for the 29-gauge needle call-out on the front of the box.

Let your specialty pharmacy know if you have any questions or concerns about the HUMIRA you receive.

Icon illustrating a PDF about the new HUMIRA Citrate-free packaging

Pediatric Crohn's disease dosing information

Important: You must pay attention to your child’s starting dose—it is different than his or her maintenance dose and is a critical part of taking HUMIRA as prescribed. The doctor will take your child's weight into consideration when deciding the appropriate dose. Your child’s first injection must be given under the supervision of a health care professional. Remember to keep HUMIRA refrigerated in its original container until ready for use.

Redesigned HUMIRA is available in Pediatric Starter Packages, which include the prefilled syringes for starting doses on Days 1 and 15. The dosing schedule for pediatric patients 6 years of age and older with Crohn’s disease (CD) is based on body weight as shown below:

If your child weighs 37 to 87 lbs

For children weighing 37 to 87 lbs, the Day 1 HUMIRA starting dose is 80 mg

For children weighing 37 to 87 lbs, the Day 15 HUMIRA starting dose is 40 mg

For children weighing 37 to 87 lbs, the Day 29 and maintenance HUMIRA dose is 20 mg

If your child weighs 88 lbs or more

For children weighing 88 or more lbs, the Day 1 HUMIRA starting dose is 160 mg

*Starting doses only for new patient starts.

For children weighing 88 or more lbs, the Day 15 HUMIRA starting dose is 80 mg

For children weighing 88 or more lbs, the Day 29 and maintenance HUMIRA dose is 40 mg

The injection experience

Although the injection might now feel different from prior HUMIRA injections, you should continue to follow the injection technique you learned from training. There is no change in how HUMIRA is stored.