How to give yourself an injection.
Watch the video to learn how.

Following these instructions is the first step to learning
how to self-inject.

Injecting a Child

Self-injecting HUMIRA offers you the freedom of being able to take your medicine in the comfort of your home. You may not have to make an appointment and travel to the doctor’s office for every dose. That’s why we want to give you all the information you need to become more familiar with self-injections.

Look over the many assistance options listed on this page. Whether your doctor has prescribed the HUMIRA Pen or the prefilled syringe, there are video demonstrations and training tools available to you when you need them.


View Transcript

Watch the self-injection demonstration video.

Select which injection option you use and then watch the demonstration video.

The video and step-by-step information should not take the place of personalized instruction with a health care professional. Do not try to inject HUMIRA yourself until you have been shown the right way to give the injection. The first injection must be given under the supervision of a health care professional.

Please read the complete injection instructions in the Patient Instructions for Use in your HUMIRA box.

For injection assistance or to speak with a nurse, call 1.800.4HUMIRA. Nurses are on call to provide injection help and assistance to patients taking HUMIRA.

Please read the HUMIRA dosing information
before starting your treatment.

If your doctor decides that you are able to give your injections at home, you should receive training by a health care professional on the right way to prepare and inject HUMIRA. Do not try to inject HUMIRA yourself until you have been shown the right way to give the injections. Your first injection must be given under the supervision of a health care professional. Remember to keep your HUMIRA refrigerated in its original container until ready for use.

You can call your doctor or 1.800.4HUMIRA (1.800.448.6472) if you have questions about giving yourself an injection. Complete injection instructions are found in the Patient Instructions for Use that comes within the HUMIRA box.

What to do if you miss a dose.

If you miss a dose, inject as soon as you remember. Then take your next dose as you would have on your originally scheduled date. If you are unsure of when to inject HUMIRA, call your doctor or pharmacist. If you're unable to give yourself the injection at any time, or a friend or family member cannot administer HUMIRA to you, call your doctor or nurse for help right away.

Important things to remember for your injection with HUMIRA:

  • Store HUMIRA in a refrigerator at 36°F to 46°F (2°C to 8°C)
    in the original container until it is used. Protect from light
  • Do not use HUMIRA if frozen, even if it has been thawed
  • The HUMIRA Pen contain glass. Do not drop or crush the Pen because the glass may break
  • Do not remove the gray cap or the plum-colored cap on the HUMIRA Pen until right before your injection
  • Keep HUMIRA, injection supplies and all other medicines
    out of the reach or children
  • When the plum-colored button on the HUMIRA Pen is pressed to give your dose of HUMIRA, you will hear a loud "click" sound:
    • You must practice injecting HUMIRA with your doctor or nurse so that you are not startled by this click when you start giving yourself the injection at home
    • The loud click sound means the start of the injection
    • You will know that the HUMIRA Pen injection has finished when the yellow marker appears fully in the window view and stops moving

These are not complete injection instructions.

Full injection instructions are available in the Patient Instructions for Use, or for injection assistance call 1.800.4HUMIRA.

Get additional injection help—at no additional cost.

Get your on-the-go travel kit

There is a wide range of injection assistance options available to HUMIRA patients through the myHUMIRA support program. You can use any or all of them at no additional cost to you. Get started by selecting the links or call 1.800.4HUMIRA.

  • In-person injection training—get step-by-step guidance from a registered nurse in your home, office, or clinic. Nurses can follow up with you for the first few months of treatment. Call 1.800.4HUMIRA
Injection training kit for HUMIRA (adalimumab)
  • The Injection Training Kit—lets you use multiple senses—hearing, sight, and touch—to create an experience to help you learn to self-inject. Get the HUMIRA Injection Training Kit now
  • On-Call Nurses—even when your doctor’s office is closed, myHUMIRA nurses are on call* to answer questions you may have. Set up a Talk to a Nurse request now

*myHUMIRA nurses are available for immediate assistance Monday through Friday from 8 AM to 8 PM ET. At all other times, nurses will return calls within 1 hour.

  • The On-the-Go Kit—allows you to pack your HUMIRA along with you for a short trip.
    The ice packs keep HUMIRA at the required temperature for a few hours.
    Order your HUMIRA On-The-Go-Kit now
HUMIRA Pen and Syringe Disposal Service
  • HUMIRA Pen and Syringe Disposal Service—sign up and we will send you a sharps container and instructions, at no additional cost to you

    • If you have not already signed up to receive a sharps container and instructions,
      click here
    • When your container is almost full click here, log in, or call 1.800.4HUMIRA to order a mail-back box for your full container or to order a new container

Put your Pen or syringe in an FDA-cleared sharps disposal container right away after use. Do not throw away (dispose of) the Pen or syringe in your household trash. Do not recycle your used sharps disposal container.

When your sharps disposal container is almost full, you will need to follow your community guidelines for the right way to dispose of it. For more information about safe sharps disposal, and for specific information about sharps disposal in the state that you live in, go to the FDA’s Web site at:

Always keep the sharps container out of the reach of children.

Ongoing support from a program built just for you.

Sign up for myHUMIRA and have access to additional services available, every step of the way.

With myHUMIRA, you'll receive the answers, assistance, and support you deserve—even if your needs change over time—to help you get the most from your treatment plan.

Experience everything myHUMIRA has to offer, including:

  • Injection Training Kit
  • HUMIRA On-the-Go Kit
  • Ongoing savings with the HUMIRA Co-pay Savings Card
  • Pen and syringe disposal
  • On-call nurse support
  • Medication Reminders
  • Insights & updates for your HUMIRA treatment

Sign up for myHUMIRA now

Your safety is important to us.
Learn about our Important Safety Information.

ABOUT HUMIRA® (adalimumab)1

Next Page: Save on HUMIRA

What is the most important information I should know about HUMIRA?

You should discuss the potential benefits and risks of HUMIRA with your doctor. HUMIRA is a TNF blocker medicine that can lower the ability of your immune system to fight infections. You should not start taking HUMIRA if you have any kind of infection unless your doctor says it is okay.

  • Serious infections have happened in people taking HUMIRA. These serious infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some people have died from these infections. Your doctor should test you for TB before starting HUMIRA, and check you closely for signs and symptoms of TB during treatment with HUMIRA. If your doctor feels you are at risk, you may be treated with medicine for TB.

  • Cancer. For children and adults taking TNF blockers, including HUMIRA, the chance of getting lymphoma or other cancers may increase. There have been cases of unusual cancers in children, teenagers, and young adults using TNF blockers. Some people have developed a rare type of cancer called hepatosplenic T-cell lymphoma. This type of cancer often results in death. If using TNF blockers including HUMIRA, your chance of getting two types of skin cancer (basal cell and squamous cell) may increase. These types are generally not life-threatening if treated; tell your doctor if you have a bump or open sore that doesn’t heal.

What should I tell my doctor BEFORE starting HUMIRA?

Tell your doctor about all of your health conditions, including if you:

  • Have an infection, are being treated for infection, or have symptoms of an infection
  • Get a lot of infections or infections that keep coming back
  • Have diabetes
  • Have TB or have been in close contact with someone with TB, or were born in, lived in, or traveled where there is more risk for getting TB
  • Live or have lived in an area (such as the Ohio and Mississippi River valleys) where there is an increased risk for getting certain kinds of fungal infections, such as histoplasmosis, coccidioidomycosis, or blastomycosis
  • Have or have had hepatitis B
  • Are scheduled for major surgery
  • Have or have had cancer
  • Have numbness or tingling or a nervous system disease such as multiple sclerosis or Guillain-Barré syndrome
  • Have or had heart failure
  • Have recently received or are scheduled to receive a vaccine. HUMIRA patients may receive vaccines, except for live vaccines
  • Are allergic to rubber, latex, or any HUMIRA ingredients
  • Are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed

Also tell your doctor about all the medicines you take. You should not take HUMIRA with ORENCIA® (abatacept), KINERET® (anakinra), REMICADE® (infliximab), ENBREL® (etanercept), CIMZIA® (certolizumab pegol), or SIMPONI® (golimumab). Tell your doctor if you have ever used RITUXAN® (rituximab), IMURAN® (azathioprine), or PURINETHOL® (mercaptopurine, 6-MP).

What should I watch for AFTER starting HUMIRA?

HUMIRA can cause serious side effects, including:

  • Serious infections. These include TB and infections caused by viruses, fungi, or bacteria. Symptoms related to TB include a cough, low-grade fever, weight loss, or loss of body fat and muscle.
  • Hepatitis B infection in carriers of the virus. Symptoms include muscle aches, feeling very tired, dark urine, skin or eyes that look yellow, little or no appetite, vomiting, clay-colored bowel movements, fever, chills, stomach discomfort, and skin rash.
  • Allergic reactions. Symptoms of a serious allergic reaction include hives, trouble breathing, and swelling of your face, eyes, lips, or mouth.
  • Nervous system problems. Signs and symptoms include numbness or tingling, problems with your vision, weakness in your arms or legs, and dizziness.
  • Blood problems. Symptoms include a fever that does not go away, bruising or bleeding very easily, or looking very pale.
  • Heart failure (new or worsening). Symptoms include shortness of breath, swelling of your ankles or feet, and sudden weight gain.
  • Immune reactions including a lupus-like syndrome. Symptoms include chest discomfort or pain that does not go away, shortness of breath, joint pain, or rash on your cheeks or arms that gets worse in the sun.
  • Liver problems. Symptoms include feeling very tired, skin or eyes that look yellow, poor appetite or vomiting, and pain on the right side of your stomach (abdomen).
  • Psoriasis (new or worsening). Symptoms include red scaly patches or raised bumps that are filled with pus.

Call your doctor or get medical care right away if you develop any of the above symptoms.

Common side effects of HUMIRA include injection site reactions (redness, rash, swelling, itching, or bruising), upper respiratory infections (sinus infections), headaches, rash, and nausea. These are not all of the possible side effects with HUMIRA. Tell your doctor if you have any side effect that bothers you or that does not go away.

Remember, tell your doctor right away if you have an infection or symptoms of an infection, including:

  • Fever, sweats, or chills
  • Muscle aches
  • Cough
  • Shortness of breath
  • Blood in phlegm
  • Weight loss
  • Warm, red, or painful skin or sores on your body
  • Diarrhea or stomach pain
  • Burning when you urinate
  • Urinating more often than normal
  • Feeling very tired

HUMIRA is given by injection under the skin.

This is the most important information to know about HUMIRA. For more information, talk to your health care provider.




HUMIRA is a prescription medicine used:

  • To reduce the signs and symptoms of:
    • Moderate to severe rheumatoid arthritis (RA) in adults. HUMIRA can be used alone, with methotrexate, or with certain other medicines. HUMIRA may prevent further damage to your bones and joints and may help your ability to perform daily activities.
    • Moderate to severe polyarticular juvenile idiopathic arthritis (JIA) in children 2 years of age and older. HUMIRA can be used alone, with methotrexate, or with certain other medicines.
    • Psoriatic arthritis (PsA) in adults. HUMIRA can be used alone or with certain other medicines. HUMIRA may prevent further damage to your bones and joints and may help your ability to perform daily activities.
    • Ankylosing spondylitis (AS) in adults.
    • Moderate to severe Crohn's disease (CD) and to achieve and maintain clinical remission in adults who have not responded well to conventional treatments. HUMIRA is also used to reduce signs and symptoms and to achieve clinical remission in these adults who have lost response to or are unable to tolerate infliximab.
    • Moderate to severe Crohn's disease (CD) and to achieve and maintain clinical remission in children 6 years of age and older when certain other treatments have not worked well enough.
  • In adults, to help get moderate to severe ulcerative colitis (UC) under control (induce remission) and keep it under control (sustain remission) when certain other medicines have not worked well enough. It is not known if HUMIRA is effective in people who stopped responding to or could not tolerate anti-TNF medicines.
  • To treat moderate to severe chronic plaque psoriasis (Ps) in adults who are ready for systemic therapy or phototherapy, and are under the care of a doctor who will decide if other systemic therapies are less appropriate.


In This Section

Dispose of HUMIRA
Pens and syringes
the right way.

Get Disposal Service

Get HUMIRA Pen and
syringe disposal with
mail-back service—
at no additional cost.

Please see the Full Prescribing Information, including the Medication Guide, for HUMIRA.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

If you cannot afford your medication, contact: or call the toll-free phone number (1-888-4PPA-NOW) for assistance.

Please see accompanying full Prescribing Information, including Patient Instructions for Use in the Medication Guide and discuss it with your doctor.

Legal Notices/Privacy Policy. Copyright 2013, AbbVie Inc., North Chicago, Illinois, U.S.A. If you have any questions about AbbVie’s website that have not been answered click here. This website and the information contained herein is intended for use by US residents only, is provided for informational purposes only and is not intended to replace a discussion with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider and consider the unique characteristics of each patient.

Reference: 1. HUMIRA Injection [package insert]. North Chicago, IL: AbbVie Inc.



Serious infections have happened in people taking HUMIRA. These serious infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some people have died from these infections. HUMIRA may increase the chance of getting lymphoma, including a rare kind, or other cancers. HUMIRA can cause serious side effects including hepatitis B infection in carriers of the virus, allergic reactions, nervous system problems, blood problems, heart failure, certain immune reactions including a lupus-like syndrome, liver problems, and new or worsening psoriasis.