If you're like some others who’ve not responded well enough to conventional treatments—like nonsteroidal anti-inflammatory drugs (NSAIDs)—and you're still experiencing symptoms, your doctor may consider other treatments such as sulfasalazine for pain and swelling in your peripheral joints, or corticosteroids to help reduce the pain and inflammation. Your doctor may also suggest a biologic treatment to help reduce the pain and stiffness in the spinal joints.
The symptoms of ankylosing spondylitis (AS), such as back pain and stiffness, may be attributed to inflammation in the joints of the spine.
HUMIRA is a biologic disease-modifying antirheumatic drug, also called a biologic DMARD, or simply "biologic." HUMIRA is a prescription medicine used to reduce the signs and symptoms of ankylosing spondylitis in adults.
The immune system can overproduce a protein called tumor necrosis factor (TNF), one source of inflammation. HUMIRA targets and helps block TNF-alpha, which contributes to the symptoms of AS.
HUMIRA is a prescription medicine used to reduce the signs and symptoms of ankylosing spondylitis in adults.View Transcript
You should discuss the potential benefits and risks of HUMIRA with your doctor. HUMIRA is a TNF blocker medicine that can lower the ability of your immune system to fight infections. You should not start taking HUMIRA if you have any kind of infection unless your doctor says it is okay.
Serious infections have happened in people taking HUMIRA. These serious infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some people have died from these infections. Your doctor should test you for TB before starting HUMIRA, and check you closely for signs and symptoms of TB during treatment with HUMIRA, even if your TB test was negative. If your doctor feels you are at risk, you may be treated with medicine for TB.
Cancer. For children and adults taking TNF blockers, including HUMIRA, the chance of getting lymphoma or other cancers may increase. There have been cases of unusual cancers in children, teenagers, and young adults using TNF blockers. Some people have developed a rare type of cancer called hepatosplenic T-cell lymphoma. This type of cancer often results in death. If using TNF blockers including HUMIRA, your chance of getting two types of skin cancer (basal cell and squamous cell) may increase. These types are generally not life-threatening if treated; tell your doctor if you have a bump or open sore that doesn’t heal.
Tell your doctor about all of your health conditions, including if you:
Also tell your doctor about all the medicines you take. You should not take HUMIRA with ORENCIA® (abatacept), KINERET® (anakinra), REMICADE® (infliximab), ENBREL® (etanercept), CIMZIA® (certolizumab pegol), or SIMPONI® (golimumab). Tell your doctor if you have ever used RITUXAN® (rituximab), IMURAN® (azathioprine), or PURINETHOL® (mercaptopurine, 6-MP).
HUMIRA can cause serious side effects, including:
Call your doctor or get medical care right away if you develop any of the above symptoms.
Common side effects of HUMIRA include injection site reactions (redness, rash, swelling, itching, or bruising), upper respiratory infections (sinus infections), headaches, rash, and nausea. These are not all of the possible side effects with HUMIRA. Tell your doctor if you have any side effect that bothers you or that does not go away.
HUMIRA is given by injection under the skin.
HUMIRA is a prescription medicine used:
HUMIRA is a prescription medicine used to reduce the signs and symptoms of ankylosing spondylitis in adults.
Serious infections have happened in people taking HUMIRA. These serious infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some people have died from these infections. HUMIRA may increase the chance of getting lymphoma, including a rare kind, or other cancers. HUMIRA can cause serious side effects including hepatitis B infection in carriers of the virus, allergic reactions, nervous system problems, blood problems, heart failure, certain immune reactions including a lupus-like syndrome, liver problems, and new or worsening psoriasis.