How HUMIRA works for ankylosing spondylitis.

Watch this short video to get a better understanding of how HUMIRA targets a specific source of inflammation that contributes to the symptoms of AS.

How HUMIRA® adalimumab works.

Here’s how HUMIRA works:

  • With AS, your body overproduces an inflammation-causing protein called tumor necrosis factor-alpha (TNF-alpha)
  • This inflammation can cause the back pain and stiffness that you are experiencing
  • HUMIRA works by targeting and blocking a specific source of inflammation that contributes to AS symptoms
  • Because TNF blockers, including HUMIRA, affect the immune system, they can lower the ability to fight infections and may cause other serious side effects

Not reaching your treatment goals?


A once-daily pill for people with active AS who have already tried a TNF blocker like HUMIRA could help.