Crohn's Activity and Severity
The course of Crohn's disease is unpredictable. Some patients may experience almost
no symptoms, then experience a sudden flare-up or begin to experience symptoms every
day. Because each patient is different, and because Crohn's does not progress in
the same way for everyone, it can be difficult to get diagnosed, and then to manage
Classification of Crohn's Disease
Mild to Moderate Crohn's Disease
A patient may have symptoms such as frequent diarrhea and abdominal pain, but can walk and eat normally
and is not experiencing dehydration, high fever, abdominal tenderness, painful mass,
obstruction, or weight loss of more than 10 percent. HUMIRA has not been approved
to treat patients with mild Crohn's disease.
Moderate to Severe Crohn's Disease
A patient may have failed treatment for mild to moderate disease OR has more pronounced
symptoms, including fever, significant weight loss, abdominal pain or tenderness,
intermittent nausea and vomiting, or significant anemia.
Severe Fulminant Crohn's Disease
A patient may have persistent symptoms despite appropriate treatment for moderate
to severe Crohn's disease OR may experience high fever, persistent vomiting, evidence of
intestinal obstruction or
abscess, or more severe weight loss. If symptoms persist or worsen, your doctor will determine the most appropriate treatment(s) for you.
HUMIRA is a prescription medicine used to reduce signs and symptoms, and to achieve and
maintain clinical remission in adults with moderate to severe
Crohn's disease who have not responded well to conventional treatments, and in these adults who have
also lost response to or are unable to tolerate infliximab.
Keep Track of Your Symptoms and How They Affect You
Gastroenterologists use the type and severity of symptoms to classify a patient's
Crohn's disease. Because the diagnosis and classification of the disease will help
determine your treatment plan, it is especially important to keep a record of your symptoms and how Crohn's symptoms affect